The study found that participants had an average of
about one sexual encounter a week and that 54% of these were with partners they
already knew. Over a quarter (27%) of these involved unprotected anal or
Participants’ age made no difference to whether they
had unprotected sex, but race did. Black men were only a third as likely to
report unprotected sex in any one encounter as men of other ethnicities (odds
ratio 0.32, p 0.01). In multivariate
analysis, however, taking age, the sexual familiarity of the partner and their
May 17, 2013
HPV Vaccine May Protect With Two Doses Instead of Three
Girls between the ages of 9 and 13 were randomized evenly to receive either three doses of Gardasil (261 girls) at 0, 2 and 6 months or two doses at 0 and 6 months (259 girls). In addition, 310 young women ages 16 to 26 received the three-dose schedule. Investigators measured antibody levels at 0, 7, 18, 24 and 36 months.
Among the girls who took two doses of the vaccine, their responses to strains 16 and 18 of HPV one month after their last vaccine dose proved...
May 16, 2013
Heavy Drinking Linked to HIV Transmissions
At the study’s baseline, the median number of drinks per week the men reported was eight, with the middle two quartiles ranging between two and 16 drinks. Thirty percent of the participants reported multiple partners with whom they had unprotected receptive anal intercourse over the previous two years. During more than 35,870 person-years of follow-up, 529 of the men contracted HIV.
The researchers deduced that moderate drinking, defined as an average of one to14 drinks per...
In Brighton Hove the proportion of new HIV diagnoses
which are made outside of sexual health and antenatal clinics has increased
from 25.7% in 2000 to 57.8% in 2012, driven by improvements in HIV testing in
primary care and community settings. Moreover, there has been a dramatic
improvement in the diagnosis of recent HIV infection.
Brighton Hove is the area of the UK with the highest
HIV prevalence after London. The analysis was presented to the British Association of
Sexual Health and HIV (BASHH) conference in Bristol yesterday.
Pre-existing connection with primary health
care is associated with more prompt diagnosis of HIV infection and an increased
likelihood of virological suppression one year after diagnosis among gay men,
investigators from the United States report in AIDS Patient Care and STDs.
The findings of the study could have
implications for ‘test and treat’ strategies currently being proposed as a way
of controlling the ongoing HIV epidemic among gay and other men who have sex
with men (MSM) in the United States and other countries....
Adding the approved HCV protease inhibitor
telaprevir (Incivo or Incivek) to pegylated interferon and
ribavirin can increase sustained viral response rates even for difficult-to-treat
liver transplant recipients, but adverse events are common, researchers reported
at the 48th International Liver Congress (EASL 2013) last month in
While many hepatitis C patients await interferon-free
direct-acting antiviral regimens, others have advanced liver disease and need
treatment now. This group includes liver transplant recipients, as HCV...
May 15, 2013
Nanoparticles May Transport HIV Meds to the Brain
The researchers bound the drug to MENs inserted into macrophage immune cells. They then used magnetic energy to draw the drug through a cell membrane manufactured as a laboratory version of the blood-brain barrier. Next the use of a low-energy electrical current prompted the drug’s release from the nanoparticle. Tests confirmed the functional and structural integrity of the drug after its release.
To read the Miami Herald story, click here.
To read the study abstract, click...
Infection with hepatitis E virus (HEV) can
cause rapid liver fibrosis in people with HIV who have low CD4 cell counts,
case reports published in the online edition of Clinical Infectious Diseases show. Spanish investigators reported
two instances of HEV infection in gay men with HIV who had severe
immunosuppression. Treatment with ribavirin monotherapy led to normalisation of
liver function and temporary suppression of HEV replication.
“Chronic HEV…can lead to cirrhosis within
less than three years,” comment the authors. “In the...